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{"title":"DCFH-DA Staining Sperm Specimen Male Fertility Test Kit Hydrogen Peroxide","imgUrl":"https:\/\/img.silkroadsl.com\/nimg\/e4\/20\/d0088f13e5863bc3b0f3f30204e9-200x200-1\/dcfh_da_staining_sperm_specimen_male_fertility_test_kit_hydrogen_peroxide_detection.jpg","attrs":{"Brand Name":"BRED","Model Number":"BRED-032","Place of Origin":"China","Minimum Order Quantity":"1 kit"}}
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Sperm Reactive Oxygen Species (ROS) Assay Kit (NBT Method)
Male Infertility Diagnosis
The kit is used for detection of sperm reactive oxygenspecies levels in adult males.
Clinical Significance
In normal physiological condition, a balance exists between ROS generation and scavenging. Limited amounts of ROS is needed to regulate normal sperm function. ROStakes an important role in sperm capacitation, sperm-oocyte fusion and etc.
If ROS production exceeds the body's purification ability, the ROS accumulation can lead to oxidative stress injury (such as peroxidation of lipids, sperm DNA and mitochondria damage, cellapoptosis), causing sperm function and vitality damage, thus negatively affect fertility.
Technical Advantages
The detection substance of this kit is the activity of superoxide anion radical of sperm, rather than the product of oxidative stress injury(such as MDA or LPO)or the indirect substances involved in ROS metabolizing enzymes(such as SOD and GSH-Px,)so it can reflect the true level of ROS more intuitively.
In good relevance with the results of chemiluminescence method
Shi Ming-hua, Li Mu-jun. Research progress on reactive oxygen species and male infertility. Chinese Journal of New Clinical Medicine.2013, 6 (5):487-491.
Damage of Reactive Oxygen Species on sperm DNA structure and the test of ROS. Chinese Medical Hearald.Wang Na, 2009,612:5-6.
Shi Ming-hua, Li Mu-jun. Research progress on reactive oxygen species and male infertility. China Journal of New Clinical Medicine.2013,605:487-491.
BRED Life Science Technology Inc. specializes in developing, manufacturing and marketing lab products in the field of reproductive medicine, offering automatic assay platform and related products for infertility diagnosis and ART treatment. Based on the test metho...
BRED Life Science Technology Inc. specializes in developing, manufacturing and marketing lab products in the field of reproductive medicine, offering automatic assay platform and related products for infertility diagnosis and ART treatment. Based on the test metho...