XI'AN NATURAL -FIELD BIO-TECHQUE CO.,LTD
| Place of Origin | China |
| Brand Name | NF |
| Certification | ISO BV HACCP |
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Product Specification
| Place of Origin | China | Brand Name | NF |
| Certification | ISO BV HACCP |
1.Basic information:
Product name: Indole-3-carbinol
Appreance: White fine powder
Chemical name: Indolemethanol; Indole-3-carbinol; 3-(Hydroxymethyl)indole; 3-Indolemethanol; 1H-Indol-3-ylmethanol; Indole-3-methanol; 1H-Indole-3-methanol
CAS No.:700-06-1
EINECS No.:211-836-2
Molecular formula :C9H9NO
Molecular weight:147.18
Purity: ≥ 99% by HPLC
Melting Point(mp):96-99°C
Loss on drying≤0.5%
Use : Nutraceuticals, or intermediate for medicines
Package : 25kg per paper barrel
Storage : Refrigerate (+4°C). Protect from light
2.Indole 3 methanol 3-Hydroxymethylindole
|
Content |
Specification |
Results |
|
Assay(HPLC) |
≥99.0% |
99.4% |
|
Melting range |
96.0-100.0 |
97.2-98.7 |
|
Residue on ignition |
0.1% |
0.04% |
|
PH |
5-8 |
6-7 |
|
Loss on drying |
1.0% |
0.46% |
|
Pb |
5ppm |
Conforms |
|
Arsenic |
1ppm |
Conforms |
|
Total plate count |
500cuf/g |
Conforms |
|
Moulds |
100cuf/g |
Conforms |
|
E .coli |
Negative |
Negative |
|
Salmonella |
Negative |
Negative |
3. Description
Indole 3 Carbinol is a type of Indole. Chemically, it is a metabolite of Glucobrassicin, which in turn is a hydrolytic product of Glucosinolates.
4.Function:
Indole-3-carbinol and its main metabolite diindoylmethane modulates several nuclear transcription factors resulting in a variety of biological and biochemical effects. Indole-3-carbinol works as a strong antioxidant, thereby protecting the DNA and other cell structures.
Chemopreventive
Indole-3-carbinol has chemopreventive activity and stimulates the production of detoxifying enzymes. The phytochemical protects against carcinogenic effect of pesticides and other toxins.
Anticancer
The anticancer effects of indole-3-carbinol and its metabolite diindoylmethane are the result of specific activities: inducing enzymes that metabolize carcinogens, enhancing DNA repair, inducing G1 cell cycle arrest and apoptosis. Indole-3-carbinol blocks estrogen receptor sites on the membranes of breast and other cells, thereby reducing the risk of cervical and breast cancer. Indole-3-carbinol increases the ratio of 2-hydroxyestrone to 16 alpha-hydroxyestrone and inhibits the 4-hydroxylation of estradiol. This is a favourable action of indole-3-carbinol because 16 alpha-hydroxyestrone and 4-hydroxyestrone have carcinogenic action. The estrogen metabolite 2-hydroxyestrone has protective against several types of cancer. Studies with animals have demonstrated that indole-3-carbinol reduced the carcinogenic affects of aflatoxins. The influence of indole-3-carbinol on the development of prostate cancer is less clear. Most studies report protective effects but a few studies indicate that indole-3-carbinol may promote prostate cancer formation. Treatment of skin cancer cells with ultraviolet-B results in the apoptosis of their apoptosis, a favorable effect that seems to be stimulated by indole-3-carbinol. Some studies also show a beneficial effect on the treatment of skin cancer.
Heart health
A few studies demonstrate the beneficial effects of indole-3-carbinol on lipid synthesis and platelet aggregation, suggesting that this phytochemical could help to improve heart health.
Company Details
Business Type:
Manufacturer,Exporter,TradingCompany
Year Established:
2005
Total Annual:
lessthan$1,000,000
Employee Number:
50-100
Ecer Certification：
Active Member
Xi'an Natural-Field Bio-Technique Co.,Ltd,founded in 2005,dedicate to the natural active ingredients and effective separation of the monomer ingredients. Our products mainly are used in pharmaceutical,health care and cosmetic industries.HISTORY:2005,Xi'an Natural-Field Bio-Technique Co.,Ltd was foun... Xi'an Natural-Field Bio-Technique Co.,Ltd,founded in 2005,dedicate to the natural active ingredients and effective separation of the monomer ingredients. Our products mainly are used in pharmaceutical,health care and cosmetic industries.HISTORY:2005,Xi'an Natural-Field Bio-Technique Co.,Ltd was foun...
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